Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar CellsSummary

Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar CellsSummary

Background & Aims: Pancreatic acinar cells have an expanded apical endosomal system, the physiologic and pathophysiologic significance of which is still emerging. Phosphatidylinositol-3,5-bisphosphate [PI(3,5)P2] is an essential phospholipid generated by phosphatidylinositol 3-phosphate 5-kinase...

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Bibliographic Details
Main Authors: Scott W. Messenger, Diana D.H. Thomas, Michelle M. Cooley, Elaina K. Jones, Michelle A. Falkowski, Benjamin K. August, Luis A. Fernandez, Fred S. Gorelick, Guy E. Groblewski
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X15001472

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http://www.sciencedirect.com/science/article/pii/S2352345X15001472

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