Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates

Abstract Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D) aggregation “self‐activates” MSCs to augment their p...

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Bibliographic Details
Main Authors: Angela W. Xie, Nicholas A. Zacharias, Bernard Y. K. Binder, William L. Murphy
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Stem Cells Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/sctm.19-0414