Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates
Abstract Human mesenchymal stromal cells (MSCs) are promising candidates for cell therapy due to their ease of isolation and expansion and their ability to secrete antiapoptotic, pro‐angiogenic, and immunomodulatory factors. Three‐dimensional (3D) aggregation “self‐activates” MSCs to augment their p...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-08-01
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Series: | Stem Cells Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/sctm.19-0414 |