Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma

Glioblastoma is the most common and aggressive brain tumor, which is uniformly lethal due to its extreme invasiveness and the absence of curative therapies. Immune checkpoint inhibitors have not yet proven efficacious for glioblastoma patients, due in part to the low prevalence of tumor-reactive T c...

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Bibliographic Details
Main Authors: Tiarne van de Walle, Alessandra Vaccaro, Mohanraj Ramachandran, Ilkka Pietilä, Magnus Essand, Anna Dimberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.724739/full