A selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice

A selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice

Rheumatoid arthritis (RA) is a chronic, inflammatory, synovitis-dominated systemic disease with unknown etiology. RA is characterized by the involvement of multiple affected joints, symmetry, and invasive arthritis of the limbs, which can lead to joint deformity, cartilage destruction, and loss of f...

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Bibliographic Details
Main Authors: Jiaxiang Bai, Gaoran Ge, Yijun Wang, Wenhao Zhang, Qing Wang, Wei Wang, Xiaobin Guo, Binqing Yu, Yaozeng Xu, Huilin Yang, Xuesong Zhu, Mingjun Wang, Dechun Geng
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Rheumatoid arthritis
Bone destruction
Inflammation
Cannabinoid receptor 2
4-quinolone-3-carboxamides CB2 agonist
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219307528

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http://www.sciencedirect.com/science/article/pii/S0753332219307528

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