Fasudil Suppresses Fibrosarcoma Growth by Stimulating Secretion of the Chemokine CXCL14/BRAK

Fasudil Suppresses Fibrosarcoma Growth by Stimulating Secretion of the Chemokine CXCL14/BRAK

We previously reported that chemokine CXCL14/BRAK (BRAK) has antitumor activity in several carcinoma cells indicating that BRAK secretion suppresses carcinoma cells. Rashomologous small GTPase (RhoA) and Rho-associated coiled-coil-containing protein kinase (ROCK) are important regulators of secretor...

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Bibliographic Details
Main Authors: Chihiro Miyamoto, Yojiro Maehata, Shigeyuki Ozawa, Takeharu Ikoma, Eiro Kubota, Kazuhito Izukuri, Yasumasa Kato, Ryu-Ichiro Hata, Masaichi-Chang-il Lee
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319304384

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http://www.sciencedirect.com/science/article/pii/S1347861319304384

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