The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection

Summary: Ebola virus (EBOV) is responsible for outbreaks with case fatality rates of up to 90% and for an epidemic in West Africa with more than ten thousand deaths. EBOV glycoprotein (EBOV-GP) is the only viral surface protein and is responsible for viral entry into cells. Here, by employing pseudo...

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Bibliographic Details
Main Authors: Gergely Imre, Verena Krähling, Madeleine Eichler, Sandra Trautmann, Nerea Ferreirós, M. Javad Aman, Fatah Kashanchi, Krishnaraj Rajalingam, Stefan Pöhlmann, Stephan Becker, Dagmar Meyer zu Heringdorf, Josef Pfeilschifter
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002340