Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology
Small molecule polyamines participate in diverse aspects of cell growth and differentiation and are known to regulate ion channel gating. Here authors reveal that cellular polyamines control nicotinic acetylcholine receptor (nAChR) biogenesis, and either catabolic degradation or inhibition of polyam...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-06-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-16629-3 |