Hypoperfusion of the Adventitial Vasa Vasorum Develops an Abdominal Aortic Aneurysm.

The aortic wall is perfused by the adventitial vasa vasorum (VV). Tissue hypoxia has previously been observed as a manifestation of enlarged abdominal aortic aneurysms (AAAs). We sought to determine whether hypoperfusion of the adventitial VV could develop AAAs. We created a novel animal model of ad...

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Bibliographic Details
Main Authors: Hiroki Tanaka, Nobuhiro Zaima, Takeshi Sasaki, Masaki Sano, Naoto Yamamoto, Takaaki Saito, Kazunori Inuzuka, Takahiro Hayasaka, Naoko Goto-Inoue, Yuki Sugiura, Kohji Sato, Hirona Kugo, Tatsuya Moriyama, Hiroyuki Konno, Mitsutoshi Setou, Naoki Unno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4550325?pdf=render