ZAK Inhibitor PLX4720 Promotes Extrusion of Transformed Cells via Cell Competition

ZAK Inhibitor PLX4720 Promotes Extrusion of Transformed Cells via Cell Competition

Summary: Previous studies have revealed that, at the initial step of carcinogenesis, transformed cells are often eliminated from epithelia via cell competition with the surrounding normal cells. In this study, we performed cell competition-based high-throughput screening for chemical compounds using...

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Bibliographic Details
Main Authors: Takeshi Maruyama, Ayana Sasaki, Sayuri Iijima, Shiyu Ayukawa, Nobuhito Goda, Keisuke Tazuru, Norikazu Hashimoto, Takashi Hayashi, Kei Kozawa, Nanami Sato, Susumu Ishikawa, Tomoko Morita, Yasuyuki Fujita
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Chemistry
Biological Sciences
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305149

Internet

http://www.sciencedirect.com/science/article/pii/S2589004220305149

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