Use of an automated pyrosequencing technique for confirmation of sickle cell disease.

Use of an automated pyrosequencing technique for confirmation of sickle cell disease.

<h4>Background</h4>The diagnosis of sickle cell disease (SCD) is made by hemoglobin assays such as high-performance liquid chromatography (HPLC), isoelectric focusing and cellulose acetate or citrate agar electrophoresis. These assays are easy to perform and used in large-scale newborn s...

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Main Authors: Camila Cruz de Martino, Cecilia Salete Alencar, Paula Loureiro, Anna Barbara de Freitas Carneiro-Proietti, Claudia de Alvarenga Máximo, Rosimere Afonso Mota, Daniela Oliveira Werneck Rodrigues, Nelson Gaburo Junior, Shannon Kelly, Ester Cerdeira Sabino, International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III)
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216020

Internet

https://doi.org/10.1371/journal.pone.0216020

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