Epigenetic, genetic and environmental interactions in esophageal squamous cell carcinoma from northeast India.

BACKGROUND:Esophageal squamous cell carcinoma (ESCC) develops as a result of complex epigenetic, genetic and environmental interactions. Epigenetic changes like, promoter hypermethylation of multiple tumour suppressor genes are frequent events in cancer, and certain habit-related carcinogens are tho...

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Bibliographic Details
Main Authors: Fazlur Rahman Talukdar, Sankar Kumar Ghosh, Ruhina Shirin Laskar, Rosy Mondal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3626640?pdf=render