Serum cytokine profiles in healthy nonhuman primates are blunted by sedation and demonstrate sexual dimorphism as detected by a validated multiplex immunoassay

Abstract Cytokine profiling is a valuable tool for monitoring immune responses associated with disease and treatment. This study assessed the impact of sex and sedation on serum cytokines in healthy nonhuman primates (NHPs). Twenty-three cytokines were measured from serum using a bead-based multiple...

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Bibliographic Details
Main Authors: Laura Hocum Stone, Scott Hunter Oppler, Julia L. Nugent, Sarah Gresch, Bernhard J. Hering, Michael P. Murtaugh, Rebecca L. Hegstad-Davies, Sabarinathan Ramachandran, Melanie L. Graham
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81953-7