Additive Effects of Mechanical Marrow Ablation and PTH Treatment on de Novo Bone Formation in Mature Adult Rats

Additive Effects of Mechanical Marrow Ablation and PTH Treatment on de Novo Bone Formation in Mature Adult Rats

Mechanical ablation of bone marrow in young rats induces rapid but transient bone growth, which can be enhanced and maintained for three weeks by the administration of parathyroid hormone (PTH). Additionally, marrow ablation, followed by PTH treatment for three months leads to increased cortical thi...

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Bibliographic Details
Main Authors: Jodi A. Carlson Scholz, Agnès Vignery, James Gilligan, Nozer Mehta, Xiaoqing Xu, Christopher Miller, Jesse Bible, Jiliang Li, Qing Zhang
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Cells
Subjects:
PTH
mechanical marrow ablation
bone engineering
aging
site-directed bone formation
Online Access:http://www.mdpi.com/2073-4409/1/4/1168

Internet

http://www.mdpi.com/2073-4409/1/4/1168

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