Copy number alteration and uniparental disomy analysis categorizes Japanese papillary thyroid carcinomas into distinct groups.

Copy number alteration and uniparental disomy analysis categorizes Japanese papillary thyroid carcinomas into distinct groups.

The aim of the present study was to investigate chromosomal aberrations in sporadic Japanese papillary thyroid carcinomas (PTCs), concomitant with the analysis of oncogene mutational status. Twenty-five PTCs (11 with BRAF(V600E), 4 with RET/PTC1, and 10 without mutation in HRAS, KRAS, NRAS, BRAF, RE...

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Main Authors: Michiko Matsuse, Kensaku Sasaki, Eijun Nishihara, Shigeki Minami, Chisa Hayashida, Hisayoshi Kondo, Keiji Suzuki, Vladimir Saenko, Koh-ichiro Yoshiura, Norisato Mitsutake, Shunichi Yamashita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3340412?pdf=render

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http://europepmc.org/articles/PMC3340412?pdf=render

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