Role of electron microscopy in the diagnosis of cadasil syndrome: a study of 32 patients.

Role of electron microscopy in the diagnosis of cadasil syndrome: a study of 32 patients.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by NOTCH3 gene mutations that result in vascular smooth muscle cell (VSMC) degeneration. Its distinctive feature by electron microscopy (EM) is granular osmiophilic material (GOM) detected...

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Bibliographic Details
Main Authors: Manrico Morroni, Daniela Marzioni, Michele Ragno, Paolo Di Bella, Elisabetta Cartechini, Luigi Pianese, Teresa Lorenzi, Mario Castellucci, Marina Scarpelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3684609?pdf=render

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http://europepmc.org/articles/PMC3684609?pdf=render

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