Epistatic interactions of genetic loci associated with age-related macular degeneration

Abstract The currently largest genome-wide association study (GWAS) for age-related macular degeneration (AMD) defines disease association with genome-wide significance for 52 independent common and rare genetic variants across 34 chromosomal loci. Overall, these loci contain over 7200 variants and...

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Bibliographic Details
Main Authors: Christina Kiel, Christoph A. Nebauer, Tobias Strunz, Simon Stelzl, Bernhard H. F. Weber
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92351-4