Punica granatum L. protects mice against hexavalent chromium-induced genotoxicity

Punica granatum L. protects mice against hexavalent chromium-induced genotoxicity

This study investigated the chemoprotective effects of Punica granatum L. (Punicaceae) fruits alcoholic extract (PGE) on mice exposed to hexavalent chromium [Cr(VI)]. Animals were pretreated with PGE (25, 50 or 75 mg/kg/day) for 10 days and subsequently exposed to a sub-lethal dose of Cr(VI) (30 mg/...

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Bibliographic Details
Main Authors: Renato Ivan de Ávila, Meirielle Teixeira Guerra, Kamilla de Almeida Souza Borges, Marcelo de Sousa Vieira, Luiz Marcos de Oliveira Júnior, Humberto Furtado, Mariana Flavia da Mota, Andréa Fernandes Arruda, Marize Campos Valadares
Format: Article
Language:English
Published: Universidade de São Paulo 2013-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Quimioprevenção
Cromo hexavalente
Dano oxidative
Romã
Punica granatum
Punicaceae
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400008&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400008&lng=en&tlng=en

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