Sporadic colorectal cancer development shows rejuvenescence regarding epithelial proliferation and apoptosis.

BACKGROUND AND AIMS: Sporadic colorectal cancer (CRC) development is a sequential process showing age-dependency, uncontrolled epithelial proliferation and decreased apoptosis. During juvenile growth cellular proliferation and apoptosis are well balanced, which may be perturbed upon aging. Our aim w...

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Bibliographic Details
Main Authors: Katalin Leiszter, Orsolya Galamb, Ferenc Sipos, Tibor Krenács, Gábor Veres, Barnabás Wichmann, Alexandra Kalmár, Árpád V Patai, Kinga Tóth, Gábor Valcz, Béla Molnár, Zsolt Tulassay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789736?pdf=render