Liver-spleen axis, insulin-like growth factor-(IGF)-I axis and fat mass in overweight/obese females

<p>Abstract</p> <p>Background</p> <p>Fat mass (FM) in overweight/obese subjects has a primary role in determining low-grade chronic inflammation and, in turn, insulin resistance (IR) and ectopic lipid storage within the liver. Obesity, aging, and FM influence the growth...

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Bibliographic Details
Main Authors: Lombardi Gaetano, Orio Francesco, Rossi Annalisa, Nedi Valeria, De Rosa Annalba, Di Somma Carolina, Pizza Genoveffa, Savastano Silvia, Colao Annamaria, Tarantino Giovanni
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/136