Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography

Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography

Organismal phenotypes frequently involve multiple organ systems. Histology is a powerful way to detect cellular and tissue phenotypes, but is largely descriptive and subjective. To determine how synchrotron-based X-ray micro-tomography (micro-CT) can yield 3-dimensional whole-organism images suitabl...

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Bibliographic Details
Main Authors: Yifu Ding, Daniel J Vanselow, Maksim A Yakovlev, Spencer R Katz, Alex Y Lin, Darin P Clark, Phillip Vargas, Xuying Xin, Jean E Copper, Victor A Canfield, Khai C Ang, Yuxin Wang, Xianghui Xiao, Francesco De Carlo, Damian B van Rossum, Patrick La Riviere, Keith C Cheng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
volumetric histology
whole-organism phenomics
3D imaging
micro-CT
zebrafish
tissue architecture
Online Access:https://elifesciences.org/articles/44898

Internet

https://elifesciences.org/articles/44898

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