Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis.

Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis.

Cyclic di-AMP is a recently discovered signaling molecule which regulates various aspects of bacterial physiology and virulence. Here we report the characterization of c-di-AMP synthesizing and hydrolyzing proteins from Mycobacterium tuberculosis. Recombinant Rv3586 (MtbDisA) can synthesize c-di-AMP...

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Bibliographic Details
Main Authors: Kasi Manikandan, Varatharajan Sabareesh, Nirpendra Singh, Kashyap Saigal, Undine Mechold, Krishna Murari Sinha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3900455?pdf=render

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http://europepmc.org/articles/PMC3900455?pdf=render

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