Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis.
Cyclic di-AMP is a recently discovered signaling molecule which regulates various aspects of bacterial physiology and virulence. Here we report the characterization of c-di-AMP synthesizing and hydrolyzing proteins from Mycobacterium tuberculosis. Recombinant Rv3586 (MtbDisA) can synthesize c-di-AMP...
Main Authors: | Kasi Manikandan, Varatharajan Sabareesh, Nirpendra Singh, Kashyap Saigal, Undine Mechold, Krishna Murari Sinha |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3900455?pdf=render |
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