Spatial signals link exit from mitosis to spindle position

In budding yeast, if the spindle becomes mispositioned, cells prevent exit from mitosis by inhibiting the mitotic exit network (MEN). The MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase Cdc14. There are two competing models that explain MEN regul...

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Bibliographic Details
Main Authors: Jill Elaine Falk, Dai Tsuchiya, Jolien Verdaasdonk, Soni Lacefield, Kerry Bloom, Angelika Amon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/14036