Discretionary Transduction of MMP-Sensitized Tousled in Head and Neck Cancer

Oral radiotoxicity is often a limiting factor in cancer treatment. Previously, we demonstrated that transfer of cell-permeable, TAT-fusion Tousled-like kinase 1B (TLK1B) protein in salivary glands effectively mitigates radiation-induced salivary dysfunction. However, similar to most radioprotectors,...

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Bibliographic Details
Main Authors: Renjith Parameswaran Nair, Prakash Srinivasan Timiri Shanmugam, Gulshan Sunavala-Dossabhoy
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300129