The neuroprotective effect of recombinant human erythropoietin via an antiapoptotic mechanism on hypoxic-ischemic brain injury in neonatal rats

The neuroprotective effect of recombinant human erythropoietin via an antiapoptotic mechanism on hypoxic-ischemic brain injury in neonatal rats

PurposeThe neuroprotective effects of erythropoietin (EPO) have been recently shown in many animal models of brain injury, including hypoxic-ischemic (HI) encephalopathy, trauma, and excitotoxicity; however, limited data are available for such effects during the neonatal periods. Therefore, we inves...

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Bibliographic Details
Main Authors: Moon Sun Kim, Yoo Kyung Seo, Hye Jin Park, Kye Hyang Lee, Kyung Hoon Lee, Eun Jin Choi, Jin Kyung Kim, Hai Lee Chung, Woo Taek Kim
Format: Article
Language:English
Published: Korean Pediatric Society 2010-10-01
Series:Korean Journal of Pediatrics
Subjects:
Erythropoietin
Apoptosis
Hypoxic-ischemic brain injury
Bcl-2
Bax
Caspase-3
Online Access:http://kjp.or.kr/upload/pdf/kjped-53-898.pdf

Internet

http://kjp.or.kr/upload/pdf/kjped-53-898.pdf

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