Usefulness of Mendelian Randomization in Observational Epidemiology

Mendelian randomization refers to the random allocation of alleles at the time of gamete formation. In observational epidemiology, this refers to the use of genetic variants to estimate a causal effect between a modifiable risk factor and an outcome of interest. In this review, we recall the princip...

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Bibliographic Details
Main Authors: Murielle Bochud, Valentin Rousson
Format: Article
Language:English
Published: MDPI AG 2010-02-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:http://www.mdpi.com/1660-4601/7/3/711/