An in vitro model for assessment of SARS-CoV-2 infectivity by defining the correlation between virus isolation and quantitative PCR value: isolation success of SARS-CoV-2 from oropharyngeal swabs correlates negatively with Cq value

An in vitro model for assessment of SARS-CoV-2 infectivity by defining the correlation between virus isolation and quantitative PCR value: isolation success of SARS-CoV-2 from oropharyngeal swabs correlates negatively with Cq value

Abstract Background At the beginning of the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), little was known about its actual rate of infectivity and any COVID-19 patient positive in laboratory testing was supposed to be highly infective and a public health risk fact...

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Bibliographic Details
Main Authors: Sonnleitner Sissy Therese, Dorighi Julian, Jansen Bianca, Schönegger Carmen, Gietl Sarah, Koblmüller Stephan, Sturmbauer Christian, Posch Wilfried, Walder Gernot
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Virology Journal
Subjects:
SARS-CoV-2
Infectivity
Transmission pattern in vitro
Quantitation of viral infectivity
Online Access:https://doi.org/10.1186/s12985-021-01542-y

Internet

https://doi.org/10.1186/s12985-021-01542-y

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