Expression of hypoxia inducible factor-1α and vascular endothelial growth factor-C in human chronic periodontitis

Background/purpose: Evidence shows that there is a relationship between hypoxia and inflammatory response in periodontitis. Hypoxia-inducible factor (HIF)-1α is a major regulator of energy homeostasis and cellular adaptation to low oxygen stress. Although experimental results demonstrate an associat...

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Bibliographic Details
Main Authors: Qing-Yan Shi, Shi-Guang Huang, Jing-Hua Zeng, Xiao-Guo Fang
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790215000537