Genome-Wide Circular RNA Expression Patterns Reflect Resistance to Immunomodulatory Drugs in Multiple Myeloma Cells

Genome-Wide Circular RNA Expression Patterns Reflect Resistance to Immunomodulatory Drugs in Multiple Myeloma Cells

Immunomodulatory drugs (IMiDs), such as lenalidomide and pomalidomide, may induce significant remissions in multiple myeloma (MM) patients, but relapses are frequently observed and the underlying molecular mechanisms for this are not completely understood. Circular RNAs (circRNAs) constitute an emer...

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Bibliographic Details
Main Authors: Theresa Jakobsen, Mette Dahl, Konstantinos Dimopoulos, Kirsten Grønbæk, Jørgen Kjems, Lasse Sommer Kristensen
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
immunomodulatory drugs
multiple myeloma
circular RNA
epigenetics
genome-wide profiling
RNA-sequencing
Online Access:https://www.mdpi.com/2072-6694/13/3/365

Internet

https://www.mdpi.com/2072-6694/13/3/365

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