Loss of HES-1 Expression Predicts a Poor Prognosis for Small Intestinal Adenocarcinoma Patients

Loss of HES-1 Expression Predicts a Poor Prognosis for Small Intestinal Adenocarcinoma Patients

Objective: Hairy and enhancer of split-1 (HES-1), which is a downstream target of the Notch signaling pathway, has been linked to KRAS mutations. HES-1 has been proposed as harboring oncogenic activity in colorectal cancer but has not been investigated in adenocarcinoma of the small intestine, where...

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Bibliographic Details
Main Authors: Jeong Won Kim, Sun-Young Jun, Kris Ylaya, Hee-Kyung Chang, Young-Ha Oh, Seung-Mo Hong, Joon-Yong Chung, Stephen M. Hewitt
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
HES-1
KRAS
prognosis
small intestine
adenocarcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01427/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01427/full

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