Synthesis of 5-Alkoxythieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine Derivatives and Evaluation of Their Anticonvulsant Activities

This work concerns the design and synthesis of novel, substituted 5-alkoxythieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine derivatives 5a–p prepared from 3-amino-2-thiophenecarboxylic acid methyl ester. The final compounds were screened for their in vivo anticonvulsant activity using maximal electros...

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Bibliographic Details
Main Authors: Shi-Ben Wang, Guang-Chun Piao, Hong-Jian Zhang, Zhe-Shan Quan
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/4/6827