SP13786 Inhibits the Migration and Invasion of Lung Adenocarcinoma Cell A549 
by Supressing Stat3-EMT via CAFs Exosomes

SP13786 Inhibits the Migration and Invasion of Lung Adenocarcinoma Cell A549 
by Supressing Stat3-EMT via CAFs Exosomes

Background and objective Fibroblast activation protein (FAP) is one of the surface markers of cancer-associated fibroblasts (CAFs) and is closely related to the malignant characterization of CAFs. SP13786 is a specific micromolecule inhibitor of FAP and this study is to investigate the effects and m...

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Bibliographic Details
Main Authors: Shushu WANG, Jiayu CUI, Kaijia ZHANG, Jinhua GU, Yuanhang ZHENG, Baogang ZHANG, Lihong SHI
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2021-06-01
Series:Chinese Journal of Lung Cancer
Subjects:
lung adenocarcinoma
sp13786
cancer-associated fibroblasts
fibroblast activation protein
exosomes
emt
stat3
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2021.104.07

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2021.104.07

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