Virus Infections on Prion Diseased Mice Exacerbate Inflammatory Microglial Response

We investigated possible interaction between an arbovirus infection and the ME7 induced mice prion disease. C57BL/6, females, 6-week-old, were submitted to a bilateral intrahippocampal injection of ME7 prion strain (ME7) or normal brain homogenate (NBH). After injections, animals were organized into...

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Main Authors: Nara Lins, Luiz Mourão, Nonata Trévia, Aline Passos, José Augusto Farias, Jarila Assunção, Amanda Quintairos, João Bento-Torres, Marcia Consentino Kronka Sosthenes, José Antonio Picanço Diniz, Pedro Fernando da Costa Vasconcelos, Cristovam Wanderley Picanço-Diniz
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/3974648