Molecular strategy to reduce in vivo collagen barrier promotes entry of NCX1 positive inducible pluripotent stem cells (iPSC(NCX¹⁺)) into ischemic (or injured) myocardium.

OBJECTIVE:The purpose of this study was to assess the effect of collagen composition on engraftment of progenitor cells within infarcted myocardium. BACKGROUND:We previously reported that intramyocardial penetration of stem/progenitor cells in epicardial patches was enhanced when collagen was reduce...

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Bibliographic Details
Main Authors: Wei Huang, Bo Dai, Zhili Wen, Ronald W Millard, Xi-Yong Yu, Kristin Luther, Meifeng Xu, Ting C Zhao, Huang-Tian Yang, Zhihua Qi, Kathleen Lasance, Muhammad Ashraf, Yigang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3749126?pdf=render