Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory

Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory

The spatial organization of the genome plays an important but unclearly defined role in gene regulation. Here, the authors integrate Hi-C, RNA-seq and ATAC-seq data to map cardiogenesis from pluripotent stem cells and describe an RBM20-dependent splicing factory assembling the TTN locus with other R...

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Bibliographic Details
Main Authors: Alessandro Bertero, Paul A. Fields, Vijay Ramani, Giancarlo Bonora, Galip G. Yardimci, Hans Reinecke, Lil Pabon, William S. Noble, Jay Shendure, Charles E. Murry
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09483-5

Internet

https://doi.org/10.1038/s41467-019-09483-5

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