Deglycosylated Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1 Signaling Pathway

Deglycosylated Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1 Signaling Pathway

Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening lung disease characterized by the proliferation of myofibroblasts and deposition of extracellular matrix that results in irreversible distortion of the lung structure and the formation of focal fibrosis. The molecular mechanism o...

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Bibliographic Details
Main Authors: Hao Ruan, Shaoyan Gao, Shuangling Li, Jiaoyan Luan, Qiuyan Jiang, Xiaohe Li, Huijun Yin, Honggang Zhou, Cheng Yang
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
deglycosylated azithromycin
pulmonary fibrosis
transforming growth factor-β1
epithelial to mesenchymal transition
inflammation
Online Access:https://www.mdpi.com/1420-3049/26/9/2820

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https://www.mdpi.com/1420-3049/26/9/2820

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