Association of alpha B-crystallin genotypes with oral cancer susceptibility, survival, and recurrence in Taiwan.

BACKGROUND: Alpha B-crystallin (CRYAB) is a protein that functions as "molecular chaperone" in preserving intracellular architecture and cell membrane. Also, CRYAB is highly antiapoptotic. Abnormal CRYAB expression is a prognostic biomarker for oral cancer, while its genomic variations and...

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Bibliographic Details
Main Authors: Da-Tian Bau, Chia-Wen Tsai, Cheng-Chieh Lin, Ru-Yin Tsai, Ming-Hsui Tsai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3168435?pdf=render