Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms.

Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms.

BACKGROUND: The HLA genes, located in the MHC region on chromosome 6p21.3, play an important role in many autoimmune disorders, such as celiac disease (CD), type 1 diabetes (T1D), rheumatoid arthritis, multiple sclerosis, psoriasis and others. Known HLA variants that confer risk to CD, for example,...

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Main Authors: Alienke J Monsuur, Paul I W de Bakker, Alexandra Zhernakova, Dalila Pinto, Willem Verduijn, Jihane Romanos, Renata Auricchio, Ana Lopez, David A van Heel, J Bart A Crusius, Cisca Wijmenga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2386975?pdf=render

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http://europepmc.org/articles/PMC2386975?pdf=render

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