Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms.
BACKGROUND: The HLA genes, located in the MHC region on chromosome 6p21.3, play an important role in many autoimmune disorders, such as celiac disease (CD), type 1 diabetes (T1D), rheumatoid arthritis, multiple sclerosis, psoriasis and others. Known HLA variants that confer risk to CD, for example,...
Main Authors: | Alienke J Monsuur, Paul I W de Bakker, Alexandra Zhernakova, Dalila Pinto, Willem Verduijn, Jihane Romanos, Renata Auricchio, Ana Lopez, David A van Heel, J Bart A Crusius, Cisca Wijmenga |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2386975?pdf=render |
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