Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders

Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders

The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically improved the diagnosis of this disease and its distinction from multiple sclerosis. Recently, a group of patients have been described who have an NMO spectrum disorder (NMOsd) and wh...

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Bibliographic Details
Main Authors: Pablo García-Miranda, Francisco J. Morón-Civanto, Maria del Mar Martínez-Olivo, Nela Suárez-Luna, Reposo Ramírez-Lorca, Lucía Lebrato-Hernández, Raquel Lamas-Pérez, Guillermo Navarro, Javier Abril-Jaramillo, Maria Isabel García-Sánchez, José Luis Casado-Chocán, Antonio José Uclés-Sánchez, Mercedes Romera, Miriam Echevarría, María Díaz-Sánchez
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
demyelinating disease
nmosd
aqps
mog
gene sequencing
immunohistochemistry
Online Access:https://www.mdpi.com/1422-0067/20/22/5810

Internet

https://www.mdpi.com/1422-0067/20/22/5810

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