miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis

miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis

miR-224 has recently emerged as a driver oncomiR in sporadic colorectal carcinogenesis, but its pathogenetic role is still controversial. A large phenotypical and molecularly characterized series of preinvasive and invasive colorectal lesions was investigated for miR-224 expression by qRT-PCR and in...

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Bibliographic Details
Main Authors: Matteo Fassan, Ri Cui, Pierluigi Gasparini, Claudia Mescoli, Vincenza Guzzardo, Caterina Vicentini, Giada Munari, Fotios Loupakis, Sara Lonardi, Chiara Braconi, Marco Scarpa, Edoardo D'Angelo, Salvatore Pucciarelli, Imerio Angriman, Marco Agostini, Renata D'Incá, Fabio Farinati, Roberta Gafà, Giovanni Lanza, Wendy L. Frankel, Carlo Maria Croce, Nicola Valeri, Massimo Rugge
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523318304224

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http://www.sciencedirect.com/science/article/pii/S1936523318304224

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