MicroRNA-26a inhibits angiogenesis by down-regulating VEGFA through the PIK3C2α/Akt/HIF-1α pathway in hepatocellular carcinoma.

MicroRNA-26a inhibits angiogenesis by down-regulating VEGFA through the PIK3C2α/Akt/HIF-1α pathway in hepatocellular carcinoma.

BACKGROUND & AIMS:microRNAs (miRNAs) have been reported to regulate angiogenesis by down-regulating the expression of pro-angiogenic or anti-angiogenic factors. The aims of this study were to investigate whether miR-26a inhibited angiogenesis by down-regulating vascular endothelial growth factor...

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Bibliographic Details
Main Authors: Zong-Tao Chai, Jian Kong, Xiao-Dong Zhu, Yuan-Yuan Zhang, Lu Lu, Jia-Min Zhou, Long-Rong Wang, Ke-Zhi Zhang, Qiang-Bo Zhang, Jian-Yang Ao, Miao Wang, Wei-Zhong Wu, Lu Wang, Zhao-You Tang, Hui-Chuan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3806796?pdf=render

Internet

http://europepmc.org/articles/PMC3806796?pdf=render

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