Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer

Suppression of gonadal testosterone synthesis represents the standard first line therapy for treatment of metastatic prostate cancer. However, in the majority of patients who develop castration-resistant prostate cancer (CRPC), it is possible to detect persistent activation of the androgen receptor...

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Bibliographic Details
Main Authors: Mark N Stein, Neal Patel, Alexander Bershadskiy, Alisa Sokoloff, Eric A Singer
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-06-01
Series:Asian Journal of Andrology
Subjects:
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=3;spage=387;epage=400;aulast=Stein