Off-label prescription: Practice and problems
Approval of a drug for clinical use requires production of data on efficacy and safety through submission of results from randomized controlled trials (RCTs), in which the new molecule is usually compared with placebo (or an active comparator) for a set of outcomes that will serve as the basis for t...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2013-09-01
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| Series: | Revista Portuguesa de Cardiologia (English Edition) |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2174204913001803 |