An epithelial serine protease, AgESP, is required for Plasmodium invasion in the mosquito Anopheles gambiae.

Plasmodium parasites need to cross the midgut and salivary gland epithelia to complete their life cycle in the mosquito. However, our understanding of the molecular mechanism and the mosquito genes that participate in this process is still very limited.We identified an Anopheles gambiae epithelial s...

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Bibliographic Details
Main Authors: Janneth Rodrigues, Giselle A Oliveira, Michalis Kotsyfakis, Rajnikant Dixit, Alvaro Molina-Cruz, Ryan Jochim, Carolina Barillas-Mury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3324419?pdf=render