Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides

Background: Therapeutic treatment options for chronic autoimmune disorders such as multiple sclerosis (MS) rely largely on the use of non-specific immunosuppressive drugs, which are not able to cure the disease. Presently, approaches to induce antigen-specific tolerance as a therapeutic approach; fo...

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Bibliographic Details
Main Authors: Jennifer Pfeil, Mario Simonetti, Uta Lauer, Bianca von Thülen, Pawel Durek, Christina Poulsen, Justyna Pawlowska, Matthias Kröger, Ralf Krähmer, Frank Leenders, Ute Hoffmann, Alf Hamann
Format: Article
Language:English
Published: SAGE Publishing 2021-08-01
Series:Therapeutic Advances in Chronic Disease
Online Access:https://doi.org/10.1177/20406223211037830