A pragmatic window of opportunity to minimise the risk of MRONJ development in individuals with osteoporosis on Denosumab therapy: a hypothesis

Abstract Denosumab is associated with the development of medication-related osteonecrosis of the jaw (MRONJ), an uncommon but severe oral side effect with a higher prevalence in metastatic cancer patients than in patients with metabolic bone fragility. Although several oral triggers can initiate MRO...

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Bibliographic Details
Main Authors: Giuseppina Campisi, Rodolfo Mauceri, Francesco Bertoldo, Vittorio Fusco, Alberto Bedogni
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Head & Face Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13005-021-00280-4