Computing H/D-Exchange rates of single residues from data of proteolytic fragments

Computing H/D-Exchange rates of single residues from data of proteolytic fragments

<p>Abstract</p> <p>Background</p> <p>Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/Deuterium exchange (sHDX) coupled to high-resolution mass analysis of the digested protein or protein complex. In sHDX experiments muta...

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Bibliographic Details
Main Authors: Althaus Ernst, Canzar Stefan, Ehrler Carsten, Emmett Mark R, Karrenbauer Andreas, Marshall Alan G, Meyer-Bäse Anke, Tipton Jeremiah D, Zhang Hui-Min
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/424

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http://www.biomedcentral.com/1471-2105/11/424

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