Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis

Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis

Lipoprotein lipase (LPL) is the only known enzyme in the capillary endothelium of peripheral tissues that hydrolizes plasma triglycerides and provides fatty acids (FAs) for their subsequent tissue uptake. Previously, we demonstrated that mice that express LPL exclusively in muscle develop essentiall...

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Bibliographic Details
Main Authors: Elke M. Wagner, Dagmar Kratky, Guenter Haemmerle, Andelko Hrzenjak, Gert M. Kostner, Ernst Steyrer, Rudolf Zechner
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Journal of Lipid Research
Subjects:
fatty acid biosynthesis
lipoprotein lipase
lipogenic enzymes
sterol regulatory element binding protein
insulin-induced gene
leptin
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319088

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http://www.sciencedirect.com/science/article/pii/S0022227520319088

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