CK2 Inhibition Prior to Status Epilepticus Persistently Enhances KCa2 Function in CA1 Which Slows Down Disease Progression

PurposeEpilepsy therapy is currently based on anti-seizure drugs that do not modify the course of the disease, i.e., they are not anti-epileptogenic in nature. Previously, we observed that in vivo casein kinase 2 (CK2) inhibition with 4,5,6,7-tetrabromotriazole (TBB) had anti-epileptogenic effects i...

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Bibliographic Details
Main Authors: Felix Schulze, Steffen Müller, Xiati Guli, Lukas Schumann, Hannes Brehme, Till Riffert, Marco Rohde, Doreen Goerss, Simone Rackow, Anne Einsle, Timo Kirschstein, Rüdiger Köhling
Format: Article
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Cellular Neuroscience
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